PREPARATION METHOD OF L-LEUCINE BY USING MICROORGANISM

摘要

The L-leucine fermentation method using Corynebacterium MS 3382 (KCTC 8509P) (I) yields 47 g/l at pH 6.8-7.5 and 1.0 vvm aeration on the medium based on 12% glucose and isoleucine 500 mg/l and histidine 300-500 mg/l. (I) is an isoleucine requiring mutant from histidine requiring Corynebacterium MS 3178 (KFCC 10011) by uv.