发明名称 |
14 and/or 15-hydroxy 6,9 hemiacetal erythromycin derivatives |
摘要 |
Disclosed are (1) a structurally novel 6,9-hemiacetal-erythromycin derivative having a hydroxyl group at at least one of the 14- and 15-positions or a salt thereof, which has an excellent gastrointestinal function promoting effect and is low in toxicity; (2) a process for preparing a 6,9-hemiacetal-erythromycin derivative having a hydroxyl group at at least one of the 14- and 15-positions or a salt thereof, which comprises reacting a 6,9-hemiacetal-erythromycin derivative or a salt thereof with an organism-derived oxidase; and (3) a gastrointestinal function promoting agent containing a 6,9-hemiacetal-erythromycin derivative having a hydroxyl group at at least one of the 14- and 15-positions or a salt thereof.
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申请公布号 |
US5470961(A) |
申请公布日期 |
1995.11.28 |
申请号 |
US19930033777 |
申请日期 |
1993.03.19 |
申请人 |
TAKEDA CHEMICAL IND., LTD.;KITASATO KENKYUSHIO |
发明人 |
HARADA, SETSUO;FUNABASHI, YASUNORI;INATOMI, NOBUHIRO;TANAYAMA, SHIGEHARU;TANIDA, SEIICHI |
分类号 |
C07H17/08;C12P19/62;(IPC1-7):C07H17/08;A61K31/70 |
主分类号 |
C07H17/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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