发明名称 THE USE OF PORPHYRIN-COMPLEX OR EXPANDED PORPHYRIN-COMPLEX COMPOUNDS AS LOCALIZATION DIAGNOSTICUM FOR INFARCTION OR NECROSIS
摘要 The invention relates to the use of porphyrin-complex or expanded porphyrin-complex compounds for the manufacture of a diagnosticum for the localization of an infarction and of a necrosis, wherein the infarction or necrosis may comprise an infarction of heart, kidney, intestine, lung, and/or brain, and wherein the porphyrin-complex compound may be Gd-MP and/or Mn-TPP. Gd-MP: Bis-Gd-DTPA-(Mesoporphyrin-IX-13, 17-bis¢2-oxo-4,7,10,10-tetra-(carboxylatomethyl)-1,4, 7,10-tetraazadecyl!-13, 17-diamide}, bis sodium salt of formula (A); Mn-TPP: Manganese-(III)-(Tetrakis-¢3!-(carboxylatomethoxy-phenyl)-p orphyrin)-acetate, tetra sodium salt of formula (B).
申请公布号 CA2189967(A1) 申请公布日期 1995.11.23
申请号 CA19952189967 申请日期 1995.05.10
申请人 SCHERING AKTIENGESELLSCHAFT 发明人 MARCHAL, GUY JACQUES FELIX;NI, YICHENG
分类号 C07D487/22;A61K49/00;A61K49/06;A61K51/04;(IPC1-7):A61K51/04 主分类号 C07D487/22
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