发明名称 |
SELENIUM CONJUGATES FOR THE PREPARATION OF FREE RADICAL PHARMACEUTICALS |
摘要 |
The invention provides a method for making a selenium-carrier conjugate by covalently attaching (i) an organic selenium compound selected from the group consisting of RSeh, Rser, Rser', RseSer and RSeSer', wherein R and R' are each an aliphatic residue containing at least one reactive group selected from the group consisting of aldehyde, amino, alcoholic, carboxylic, phosphate, sulfate, halogen or phenolic reactive groups and combinations thereof, to (ii) a carrier having a constituent capable of forming a covalent bond with said reactive groups of said selenium compound to produce a selenium-carrier conjugate which is capable of specific attachment to a target site. |
申请公布号 |
WO9531218(A1) |
申请公布日期 |
1995.11.23 |
申请号 |
WO1995US05997 |
申请日期 |
1995.05.12 |
申请人 |
SPALLHOLZ, JULIAN, E.;REID, TED, W. |
发明人 |
SPALLHOLZ, JULIAN, E.;REID, TED, W. |
分类号 |
A61K31/095;A61K31/13;A61K33/04;A61K47/48 |
主分类号 |
A61K31/095 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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