THE USE OF PORPHYRIN-COMPLEX OR EXPANDED PORPHYRIN-COMPLEX COMPOUNDS AS LOCALIZATION DIAGNOSTICUM FOR INFARCTION OR NECROSIS

摘要

The invention relates to the use of porphyrin-complex or expanded porphyrin-complex compounds for the manufacture of a diagnosticum for the localization of an infarction and of a necrosis, wherein the infarction or necrosis may comprise an infarction of heart, kidney, intestine, lung, and/or brain, and wherein the porphyrin-complex compound may be Gd-MP and/or Mn-TPP. Gd-MP: Bis-Gd-DTPA-{Mesoporphyrin-IX-13, 17-bis[2-oxo-4,7,10,10-tetra-(carboxylatomethyl)-1,4,7,10-tetraazadecyl]-13, 17-diamide}, bis sodium salt of formula (A); Mn-TPP: Manganese-(III)-{Tetrakis-[3]-(carboxylatomethoxy-phenyl)-porphyrin}-acetate, tetra sodium salt of formula (B).