发明名称 |
MATRIX SYSTEM FOR THE TRANSDERMAL DELIVERY OF IBUPROFEN, AND METHOD FOR PREPARING SAME |
摘要 |
The invention relates to a self-adhesive transdermal matrix system for the transdermal delivery of ibuprofen, in which matrix system, which comprises acarrier and a self-adhesive matrix, said matrix includes: (a) 55 to 75 parts by weight of an adhesive acrylate copolymer with a glass transition temperature of between -70 and -10.degree.C, (b) 5 to 15 parts by weight of a cationic acrylate copolymer with a glass transition temperature of between 20 and 80.degree.C, (c) 5 to 15 parts by weight of ibuprofen in the form of the free acid, and (d) 10 to 25 parts by weight of diethyl phthalate. It further relates to a method of preparing such a matrix system.
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申请公布号 |
CA2189970(A1) |
申请公布日期 |
1995.11.23 |
申请号 |
CA19952189970 |
申请日期 |
1995.05.10 |
申请人 |
LABORATOIRES D'HYGIENE ET DE DIETETIQUE |
发明人 |
SAWAYA, ANTOINE;MATH, MARIE-CHRISTINE |
分类号 |
A61K9/70;A61K31/19;A61K31/194;A61K47/32;A61P29/00;(IPC1-7):A61K31/19 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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