发明名称 MATRIX SYSTEM FOR THE TRANSDERMAL DELIVERY OF IBUPROFEN, AND METHOD FOR PREPARING SAME
摘要 The invention relates to a self-adhesive transdermal matrix system for the transdermal delivery of ibuprofen, in which matrix system, which comprises acarrier and a self-adhesive matrix, said matrix includes: (a) 55 to 75 parts by weight of an adhesive acrylate copolymer with a glass transition temperature of between -70 and -10.degree.C, (b) 5 to 15 parts by weight of a cationic acrylate copolymer with a glass transition temperature of between 20 and 80.degree.C, (c) 5 to 15 parts by weight of ibuprofen in the form of the free acid, and (d) 10 to 25 parts by weight of diethyl phthalate. It further relates to a method of preparing such a matrix system.
申请公布号 CA2189970(A1) 申请公布日期 1995.11.23
申请号 CA19952189970 申请日期 1995.05.10
申请人 LABORATOIRES D'HYGIENE ET DE DIETETIQUE 发明人 SAWAYA, ANTOINE;MATH, MARIE-CHRISTINE
分类号 A61K9/70;A61K31/19;A61K31/194;A61K47/32;A61P29/00;(IPC1-7):A61K31/19 主分类号 A61K9/70
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