| 发明名称 |
Cholesterol lowering compound |
| 摘要 |
PCT No. PCT/US92/06520 Sec. 371 Date Feb. 2, 1994 Sec. 102(e) Date Feb. 2, 1994 PCT Filed Aug. 5, 1992 PCT Pub. No. WO93/03038 PCT Pub. Date Feb. 18, 1993.A compound of structural formula <IMAGE> having antihypercholesterolemic utility is produced by culturing a Streptomyces sp. in a nutrient medium in the presence of a substrate of structural formula: <IMAGE>
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| 申请公布号 |
US5468771(A) |
申请公布日期 |
1995.11.21 |
| 申请号 |
US19940190110 |
申请日期 |
1994.02.02 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
GAGLIARDI, MAGDA M.;CHEN, SHIEH-SHUNG T.;ARISON, BYRON H.;GARRITY, GEORGE M.;HUANG, LEEYUAN;MACCONNELL, JOHN G.;WHITE, RAYMOND F. |
| 分类号 |
C07D493/08;C07H19/01;C12P17/18;C12P19/02;(IPC1-7):A61K31/35;C07D319/04 |
主分类号 |
C07D493/08 |
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