发明名称 AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE
摘要 A compound of formula (I), wherein R<1> and R<2> are independently selected from chloro, fluoro, bromo, C1-6 alkyl, C1-6 alkoxy or C1-6 haloalkyl provided that both R<1> and R<2> are not fluoro; R<3> and R<4> are independently selected from hydrogen and C1-6 alkyl, and pharmaceutically acceptable salts, solvates or physiologically functional derivatives thereof, their use in medicine, particularly the phrophylaxis or treatment of conditions associated with inflammation, arthritis, or pain, pharmaceutical compositions comprising them, and processes for their preparation are disclosed.
申请公布号 WO9530645(A1) 申请公布日期 1995.11.16
申请号 WO1995GB01040 申请日期 1995.05.09
申请人 THE WELLCOME FOUNDATION LIMITED;MUSSO, DAVID, LEE;KELLEY, JAMES, LEROY 发明人 MUSSO, DAVID, LEE;KELLEY, JAMES, LEROY
分类号 A61K31/165;A61K31/24;A61P25/04;A61P29/00;C07C;C07C17/14;C07C45/46;C07C53/136;C07C53/23;C07C57/42;C07C57/58;C07C57/60;C07C57/62;C07C57/76;C07C59/48;C07C59/54;C07C59/56;C07C59/64;C07C69/65;C07C69/732;C07C231/02;C07C231/12;C07C233/11;C07C235/34;(IPC1-7):C07C233/11 主分类号 A61K31/165
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