发明名称 |
AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE |
摘要 |
A compound of formula (I), wherein R<1> and R<2> are independently selected from chloro, fluoro, bromo, C1-6 alkyl, C1-6 alkoxy or C1-6 haloalkyl provided that both R<1> and R<2> are not fluoro; R<3> and R<4> are independently selected from hydrogen and C1-6 alkyl, and pharmaceutically acceptable salts, solvates or physiologically functional derivatives thereof, their use in medicine, particularly the phrophylaxis or treatment of conditions associated with inflammation, arthritis, or pain, pharmaceutical compositions comprising them, and processes for their preparation are disclosed.
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申请公布号 |
WO9530645(A1) |
申请公布日期 |
1995.11.16 |
申请号 |
WO1995GB01040 |
申请日期 |
1995.05.09 |
申请人 |
THE WELLCOME FOUNDATION LIMITED;MUSSO, DAVID, LEE;KELLEY, JAMES, LEROY |
发明人 |
MUSSO, DAVID, LEE;KELLEY, JAMES, LEROY |
分类号 |
A61K31/165;A61K31/24;A61P25/04;A61P29/00;C07C;C07C17/14;C07C45/46;C07C53/136;C07C53/23;C07C57/42;C07C57/58;C07C57/60;C07C57/62;C07C57/76;C07C59/48;C07C59/54;C07C59/56;C07C59/64;C07C69/65;C07C69/732;C07C231/02;C07C231/12;C07C233/11;C07C235/34;(IPC1-7):C07C233/11 |
主分类号 |
A61K31/165 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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