METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS

摘要

Disclosed is a method of fluorescent detection of a nucleic acid. The method comprises contacting to the nucleic acid a bis-dicationic aryl furan compound, such as 2,5-bis¢4-(4, 5, 6, 7 tetrahydro-1H-1,3-diazepin-2-yl)phenyl!furan; 2,5-bis?¢4-(N-isopropyl)amidino!phenyl}furan; and physiogically acceptable salts thereof,and exposing the nucleic acid to light at a frequency to induce fluorescence of the compound. A method for fluorescent detection of cytoskeleton elements, and novel bis-dicationic aryl furan compounds are also disclosed.