发明名称 Pyrrolopyrimidine derivatives with antiproliferative action.
摘要 Use of pyrrolo(2,3-d)pyrimidine derivs. of formula (I) or their salts to prepare medicaments for treatment of tumours and other proliferative diseases, disorders of the immune system mediated by protein-tyrosine and/or protein-threonine kinases, and disorders of the central and peripheral nervous system involving signal transmission by protein-tyrosine and/or protein-threonine kinases, is new: n = 0-5; R = halo, alkyl, CF3 or alkoxy; and R1,R2 = H, alkyl, or phenyl opt. substd. by halo, CF3, alkyl or alkoxy; or R1+R2 = opt. alkyl-substd. 2-5C alkylene; provided that R1 and R2 are not both H.
申请公布号 EP0682027(A1) 申请公布日期 1995.11.15
申请号 EP19950810271 申请日期 1995.04.25
申请人 CIBA-GEIGY AG 发明人 TRAXLER, PETER, DR.;FURET, PASCAL, DR.;BRILL, WOLFGANG K.D., DR.
分类号 C07D498/02;A61K31/495;A61K31/505;A61K31/519;A61P17/06;A61P35/00;A61P37/02;A61P43/00;C07D;C07D207/18;C07D239/42;C07D487/04 主分类号 C07D498/02
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