Aziridine derivatives, their production and use

摘要

PCT No. PCT/JP95/00718 Sec. 371 Date Sep. 5, 1995 Sec. 102(e) Date Sep. 5, 1995 PCT Filed Apr. 12, 1995 PCT Pub. No. WO95/28416 PCT Pub. Date Oct. 26, 1995The present invention relates to a compound of the formula: [I] wherein R1 and Q are independently an optionally esterified or amidated carboxyl group; R2 is hydrogen, an acyl group or an optionally substituted hydrocarbon residue; X is a divalent hydrocarbon residue which may be substituted; or a salt thereof, which is useful as prophylactic and therapeutic agents of bone diseases and as agents for inhibiting thiol protease.