| 摘要 |
A spiro compound represented by general formula (I), a salt thereof, a hydrate thereof, or a solvate thereof, a typical example of which is the compound (a). It has an antagonistic effect against tachykinin receptors, especially substance P and/or neurokinin A receptors, and is useful as a preventive or remedy for respiratory diseases, central nervous system diseases, pains, and inflammatory diseases. |
