发明名称 |
METHOD FOR CONTROLLING METALLOPHOSPHATE PRECIPITATION IN HIGH CELL DENSITY FERMENTATIONS |
摘要 |
The invention relates to the use of a phosphate glass as a phosphorous source in the media of high cell density bacterial fermentation processes in order to reduce metallophosphate precipitation reactions. The methods of the invention demonstrate a practical method for controlling levels of metallophosphate precipitation in both the nutrient media and the fermentor which also result in increased cell densities and are useful in a variety of high cell density bacterial fermentation processes.
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申请公布号 |
WO9529986(A1) |
申请公布日期 |
1995.11.09 |
申请号 |
WO1995US05294 |
申请日期 |
1995.04.27 |
申请人 |
AMGEN INC. |
发明人 |
CURLESS, CRAIG, ERIC;BACLASKI, JEFFREY, BURKE |
分类号 |
C12P21/00;C07K14/50;C12N1/38;C12P21/02;(IPC1-7):C12N1/38 |
主分类号 |
C12P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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