发明名称 |
MORPHOGENIC PROTEIN-SPECIFIC CELL SURFACE RECEPTORS AND USESTHEREFOR |
摘要 |
Disclosed are (1) nucleic acid sequences, amino acid sequences, homologies, structural features and various other data characterizing a morphogen cell surface receptors particularly OP-1-binding cell surface receptors; (2) methods for producing receptor proteins, including fragments thereof, using recombinant DNA technology; (3) methods for identifying novel morphogen receptors and their encoding DNAs; (4) methods and compositions for identifying compounds capable of modulating endogenous morphogen receptor levels; and (5) methods and compositions for identifying morphogen receptor binding analogs useful in the design of morphogen agonists and antagonists for therapeutic, diagnostic and experimental uses.
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申请公布号 |
CA2187902(A1) |
申请公布日期 |
1995.11.09 |
申请号 |
CA19952187902 |
申请日期 |
1995.04.28 |
申请人 |
CREATIVE BIOMOLECULES, INC.;LUDWIG INSTITUTE FOR CANCER RESEARCH (THE) |
发明人 |
DIJKE, PETER T.;MIYAZANO, KOHEI;SAMPATH, KUBER T.;HELDIN, CARL-HENRIK |
分类号 |
G01N33/566;A61K38/00;C07K14/51;C07K14/675;C07K14/705;C07K14/71;C12N15/00;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12Q1/02;C12R1/91;G01N33/53;G01N33/567;G01N33/68;G01N33/74;(IPC1-7):C07K14/71;C07K16/22;C07K16/28 |
主分类号 |
G01N33/566 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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