Method of protein and peptide cleavage

摘要

In a method of cleaving a protein or peptide in an Asn-Gly bond thereof, the protein or peptide is treated with a compound of the general formula (I): R1-(CH2)n-NH-(CH2)m-R2, wherein R1 is NH2 or OH, R2 is hydrogen, lower alkyl, NH2, OH or halo, n is an integer from 1 to 3, and m is 0 or an integer from 1 to 3.