| 摘要 |
This relates to a manufacturing method of p-alkoxy-beta-phenylacrylic acid of formula. In formula, R1 is C1-3 hydrocarbon. This compd. is prepared by debromohydrogenation of 1-bromo-2-(4-methoxyphenyl)propionic acid with base in an organic solvent. The solvent is such as chloroform, dichloromethane and tetrahydrofuran, the reaction temp is 15-100deg.C, and the reaction time is 10-24hrs. The ratio of the reactant and the base is 1:2-1:10 eq.
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