PROPENONE DERIVATIVE.

摘要

A propenone derivative represented by general formula (I) and a pharmacologically acceptable salt thereof, wherein R<1> represents hydrogen, lower alkyl, lower alkanoyl, lower alkoxycarbonyl, lower alkylsulfonyl, aralkyl, (un)substituted aroyl, (un)substituted arylsulfonyl, (un)substituted heteroarylcarbonyl, (un)substituted heteroarylsulfonyl, diglycolyl or a group of formula (a), R<2> represents hydrogen, lower alkyl, halogen, (un)substituted aryl or (un)substituted heteroaryl; R<3> represents hydrogen, lower alkyl or (un)substituted aryl; and R<4>, R<5>, R<6> and R<7> represent each independently hydrogen, lower alkyl, lower alkoxy, aralkyloxy, hydroxy, nitro, halogen, trifluoromethyl or -NR<8>R<9>, wherein R<8> and R<9> represent each independently hydrogen, lower alkyl, lower alkanoyl, lower alkoxycarbonyl or (un)substituted aroyl. <CHEM>