Dry crystals of alpha-L-aspartyl-L-phenylalanine methyl ester having improved solubility.

摘要

Dry IB type crystals of alpha -L-aspartyl-L-phenylalanine methyl ester having improved solubility may be obtained by a process, wherein (a) the crystallization of alpha -L-aspartyl-L-phenylalanine methyl ester is carried out without causing a forced liquid flow in the crystallization medium, (b) the formed crystals are separated from the crystallization medium and subjected to a dewatering treatment to obtain wet crystals having a water content of not more than 50 wt.%, based on the overall weight of the wet crystals of alpha -L-aspartyl-L-phenylalanine methyl ester, and (c) the obtained wet crystals having a water content of not more than 50 wt.% are continuously air dried by a pneumatic conveyor dryer with hot air.