发明名称 |
2-thioindoles (selenoindoles) and related disulfides (selenides) which inhibit protein tyrosine kinases and which have antitumor properties |
摘要 |
2-Thioindoles (2-selenoindoles) and analogous 2-indolinethione (2-indolineselenone) and polysulfide (selenide) compounds, salts thereof, methods of production, intermediates in their production, pharmaceutical compositions containing said compounds, and methods for inhibiting protein kinase dependent disease in a mammal or treating aberrant cell growth in a mammal, using said compositions, are disclosed.
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申请公布号 |
US5464861(A) |
申请公布日期 |
1995.11.07 |
申请号 |
US19930094792 |
申请日期 |
1993.08.09 |
申请人 |
WARNER-LAMBERT |
发明人 |
DOBRUSIN, ELLEN M.;SHOWALTER, HOWARD D. H.;DENNY, WILLIAM A.;PALMER, BRIAN D.;REWCASTLE, GORDON W.;TERCEL, MOANA;THOMPSON, ANDREW M. |
分类号 |
A61K31/40;A61K31/403;A61K31/404;A61K31/405;A61K31/44;A61P9/00;A61P9/10;A61P31/12;A61P35/00;A61P43/00;C07D209/30;C07D209/42;C07D401/12;C07D405/12;C07D409/12;C07D471/04;(IPC1-7):A61K31/40;C07D209/04 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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