发明名称 |
Bovine basic fibroblast growth factor |
摘要 |
Substantially pure mammalian basic fibroblast growth factors are produced. The amino acid residue sequences of bovine and human bFGF are disclosed as well as a DNA chain encoding the polypeptide of the bovine species. By appropriately inserting a synthesized DNA chain into a cloning vector and using the cloning vector to transform cells, synthetic bovin bFGF can be obtained from transformed cell lines, both prokaryotic and eukaryotic.
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申请公布号 |
US5464774(A) |
申请公布日期 |
1995.11.07 |
申请号 |
US19870139953 |
申请日期 |
1987.12.31 |
申请人 |
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES |
发明人 |
BAIRD, ANDREW J.;ESCH, FREDERICK S.;GOSPODAROWICZ, DENIS;BOHLEN, PETER;LING, NICHOLAS C. |
分类号 |
A61K38/00;C07K14/50;(IPC1-7):C12N15/18 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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