摘要 |
Pt(IV) complexes of formula I, <CHEM> where X is halide, pseudohalide or OH, R<1> and R<2> are H, C1 to C6 alkyl, cycloalkyl, aryl or R<1>NH2 is a heterocyclic hydrogen donor, and may be the same or different, R<3> and R<4> are H, C1 to C5 alkyl, cycloalkyl or aryl and may be the same or different, and R<5> is H, Me or Et, have activity in vitro and in vivo against cancer cells. |