发明名称 Polyethylene protein conjugates
摘要 The present invention relates to physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugates having at least part of the biological activity of the protein which forms the conjugate, without exhibiting the same disadvantageous immunogenic responses thereof.
申请公布号 SI9210294(A) 申请公布日期 1995.10.31
申请号 SI19920010294 申请日期 1992.03.24
申请人 F. HOFFMANN-LA ROCHE AG 发明人 HAKIMI JOHN;KILIAN PATRICIA;ROSEN PERRY
分类号 A61K38/00;A61K;A61K31/745;A61K38/16;A61K38/19;A61K38/20;A61K38/21;A61K39/00;A61K39/38;A61K39/385;A61K47/42;A61K47/48;A61P37/00;A61P37/02;A61P43/00;C07C267/00;C07C331/18;C07C331/20;C07D211/04;C07D213/63;C07D213/64;C07D213/643;C07D213/70;C07D213/83;C07D213/89;C07K;C07K1/00;C07K14/47;C07K14/52;C07K14/54;C07K14/545;C07K14/55;C07K14/555;C07K14/56;C07K14/765;C07K17/00;C07K17/02;C07K17/06;C07K17/08;C07K17/10;C08F116/02;C08F216/00;C08G65/02;C08G65/08;C08G65/26;C08G65/28;C08G65/32;C08G65/34;C08G65/48;C08H1/00;C08L23/36;C08L71/02;C12N9/96;(IPC1-7):C07K17/10 主分类号 A61K38/00
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