发明名称 |
Method of preparing etoposide |
摘要 |
The present invention relates to a method of increasing the yield of etoposide produced relative to prior art processes. A residue obtained as a result of reacting etoposide triacetate with a first lower alkanol in the presence of a first transesterification catalyst is provided. This residue is then reacted with a second lower alkanol and a second transesterification catalyst.
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申请公布号 |
US5463040(A) |
申请公布日期 |
1995.10.31 |
申请号 |
US19940266923 |
申请日期 |
1994.06.28 |
申请人 |
TEVA PHARMACEUTICAL INDUSTRIES, LTD. |
发明人 |
VOGEL, CALVIN |
分类号 |
C07H17/04;(IPC1-7):A61K31/70;C07H15/20;C07H15/26 |
主分类号 |
C07H17/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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