1- beta -methyl-2-thiolic carbapenem derivatives

摘要

The present invention relates to new 1- beta -methyl-2-thiolic carbapenem derivatives represented by the following general formula (I) and producing method thereof. <IMAGE> (I) The above-mentioned compound is very stable against DHP-1 enzyme due to effective shielding of carbapenem ring structually and is highly effective in both gram-positive and gram-negative microorganism, especially has a remarkable effect on the Pseudomonas aeruginosa known as a disease germ having strong resistance.