发明名称 |
Inhibition of leukocyte adhesion |
摘要 |
This invention relates to the inhibition of intercellular adhesion mediated by L-selectin by administering a newly identified L-selectin ligand, CD34. More particularly, the invention concerns a method for inhibiting leukocyte adhesion to endothelial cells by administering an effective amount of an isolated, purified CD34 polypeptide or an antibody capable of binding native CD34. |
申请公布号 |
ZA9402956(B) |
申请公布日期 |
1995.10.30 |
申请号 |
ZA19940002956 |
申请日期 |
1994.04.28 |
申请人 |
GENENTECH, INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
LAURENCE A LASKY;SUSANNE BAUMHUETER;STEVEN D ROSEN;MARK S SINGER |
分类号 |
C12P21/08;A61K38/00;A61K39/395;A61P7/00;A61P11/00;A61P13/02;A61P15/00;A61P17/00;A61P29/00;A61P35/00;A61P37/00;A61P43/00;C07K14/47;C07K14/705;C07K16/18;C07K16/28 |
主分类号 |
C12P21/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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