| 发明名称 |
INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE AND PROCESS FOR PREPARING THEREOF |
| 摘要 |
Disclosed is a compound containing a 2-amino-7-(substituted methyl)-3_H,5_H-pyrrolo[3,2-d]pyrimidin-4-one wherein substituted methyl is -CH2-R wherein R is an optionally substituted heteroalicyclic group, a pharmaceutical composition containing the compound, and a method for the selective suppression of mammalian T-cell function without diminished effect on humoral immunity which involves administering the composition to a mammal. |
| 申请公布号 |
LT3448(B) |
申请公布日期 |
1995.10.25 |
| 申请号 |
LTIP539 |
申请日期 |
1993.05.12 |
| 申请人 |
BIOCRYST PHARMACEUTICALS, INC. |
发明人 |
SECRIST,III,JOHN A.;ERION,MARK DAVID;MONTGOMERY,JOHN A.;EALICK,STEVEN E.;GUIDA,WAYNE C.;NIWAS,SHRI |
| 分类号 |
C07C255/31;C07C255/35;C07C255/40;C07C255/42;C07D207/34;C07D487/04 |
主分类号 |
C07C255/31 |
| 代理机构 |
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