发明名称 |
Temporary living skin replacement |
摘要 |
The present invention relates to a living skin replacement. In particular, it relates to a biosynthetic dressing material composed of a living stromal tissue prepared from stromal cells such as fibroblasts cultured upon a three-dimensional framework and a transitional covering which acts as an epidermal replacement. Such a living skin replacement provides long-term biologic coverage of full-thickness wound defects. Since human fibroblasts are known to be relatively non-antigenic when transferred to allogeneic hosts, a temporary living skin replacement made up of such cells attached to a transitional covering may replace the use of cadaveric skin allografts for achieving temporary wound closure in cases where the patients lack enough healthy skin for autografts.
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申请公布号 |
US5460939(A) |
申请公布日期 |
1995.10.24 |
申请号 |
US19940200140 |
申请日期 |
1994.02.18 |
申请人 |
ADVANCED TISSUE SCIENCES, INC. |
发明人 |
HANSBROUGH, JOHN F.;NAUGHTON, GAIL K. |
分类号 |
A61B10/00;A61B10/02;A61B19/00;A61K35/12;A61K35/28;A61L27/38;A61L27/60;C12N5/00;C12N5/071;C12N5/077;C12N5/0789;(IPC1-7):C12N11/00;A61F2/10;C12M3/00 |
主分类号 |
A61B10/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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