发明名称 |
Bone-related carboxypeptidase-like protein and process for its production |
摘要 |
A bone-related carboxypeptidase-like protein named OSF-5 which is obtained from bone tissue of a mammal including mouse or human, and a process for its production. This protein is a novel naturally occurring mammal protein which belongs to a group of carboxypeptidase molecules. OSF-5 acts as an adhesion molecule or a growth factor which takes part in the process of osteogenesis at the site of bone induction. OSF-5 can be used as an agent for treating bone metabolic diseases, and its high organ specificity for bones enables its use as a diagnostic reagent for bone metabolic diseases.
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申请公布号 |
US5460951(A) |
申请公布日期 |
1995.10.24 |
申请号 |
US19930111939 |
申请日期 |
1993.08.26 |
申请人 |
HOECHST JAPAN LIMITED |
发明人 |
KAWAI, SHINJI;TAKESHITA, SUNAO;OKAZAKI, MAKOTO;AMANN, EGON |
分类号 |
A61K38/00;A61K39/395;A61P3/00;A61P19/10;A61P43/00;C07K14/00;C07K14/005;C07K14/195;C07K14/435;C07K14/47;C07K16/00;C07K16/18;C12N9/48;C12N15/09;C12N15/12;C12N15/57;C12P21/08;G01N33/53;G01N33/577;(IPC1-7):C12P21/00;C12P21/02 |
主分类号 |
A61K38/00 |
代理机构 |
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