发明名称 Bone-related carboxypeptidase-like protein and process for its production
摘要 A bone-related carboxypeptidase-like protein named OSF-5 which is obtained from bone tissue of a mammal including mouse or human, and a process for its production. This protein is a novel naturally occurring mammal protein which belongs to a group of carboxypeptidase molecules. OSF-5 acts as an adhesion molecule or a growth factor which takes part in the process of osteogenesis at the site of bone induction. OSF-5 can be used as an agent for treating bone metabolic diseases, and its high organ specificity for bones enables its use as a diagnostic reagent for bone metabolic diseases.
申请公布号 US5460951(A) 申请公布日期 1995.10.24
申请号 US19930111939 申请日期 1993.08.26
申请人 HOECHST JAPAN LIMITED 发明人 KAWAI, SHINJI;TAKESHITA, SUNAO;OKAZAKI, MAKOTO;AMANN, EGON
分类号 A61K38/00;A61K39/395;A61P3/00;A61P19/10;A61P43/00;C07K14/00;C07K14/005;C07K14/195;C07K14/435;C07K14/47;C07K16/00;C07K16/18;C12N9/48;C12N15/09;C12N15/12;C12N15/57;C12P21/08;G01N33/53;G01N33/577;(IPC1-7):C12P21/00;C12P21/02 主分类号 A61K38/00
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