发明名称 |
PHARMACEUTICALS MICROENCAPSULATED BY VAPOR DEPOSITED POLYMERS AND METHOD |
摘要 |
A microencapsulated pharmaceutical is formed by vapor depositing a polymeric film about an active pharmaceutical agent. The film thickness of the vapor deposited film is controlled to provide effective controlled release of said pharmaceutical agent subsequent to application. In a preferred embodiment the pharmaceutical is an orally ingestible pharmaceutical formed by vapor deposition of a poly-p-xylylene polymer about a core comprising an active pharmaceutical agent. The pharmaceutical agent exhibits surprising controlled release activity inspite of the extreme inertness of vapor deposited films such as Parylene films.
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申请公布号 |
CA1337398(C) |
申请公布日期 |
1995.10.24 |
申请号 |
CA19890610931 |
申请日期 |
1989.09.11 |
申请人 |
RONALD T. DODGE COMPANY (THE) |
发明人 |
VERSIC, RONALD J.;SELENKE, WILLIAM M. |
分类号 |
A61K9/22;A61K9/32;A61K9/50;(IPC1-7):A61K9/50;B01J13/02;A61K9/58 |
主分类号 |
A61K9/22 |
代理机构 |
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