Separation of acetaldehyde-induced hemoglobin (Hb A1-AcH)

摘要

A chromatographic method used to detect chronic alcohol usage and alcoholism and to monitor alcohol rehabilitation treatment; the method provides improved resolution of the Hb A1-AcH peak from the contiguous Hb A1c peak by means of a polyaspartic acid chromatographic column and a nonlinear buffer gradient; the resulting Hb A1-AcH peak is then evaluated to determine chronic alcohol usage which is indicative of alcoholism and which can be used to monitor alcohol rehabilitation treatment.