| 发明名称 |
CIRCULARLY PERMUTED LIGANDS AND CIRCULARLY PERMUTED CHIMERIC MOLECULES |
| 摘要 |
The present invention provides for circularly permuted ligands which possess specificity and binding affinity comparable to or greater than the specificity and binding affinity of the original (unpermuted) ligand. The invention further provides for novel chimeric molecules comprising a circularly permuted ligand joined to one or more molecules of interest.
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| 申请公布号 |
CA2187283(A1) |
申请公布日期 |
1995.10.19 |
| 申请号 |
CA19952187283 |
申请日期 |
1995.04.07 |
| 申请人 |
GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (THE) |
发明人 |
PURI, RAJ K.;KREITMAN ROBERT J;PURI RAJ K |
| 分类号 |
A61K38/00;A61K47/48;C07K1/107;C07K14/535;C07K14/54;C07K14/55;C07K16/30;C12N15/62;(IPC1-7):C07K19/00;A61K38/16;A61K38/19;A61K38/20 |
主分类号 |
A61K38/00 |
| 代理机构 |
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