TREATMENT OF AUTOIMMUNE DISEASE USING ORAL TOLERIZATION AND/OR TYPE I INTERFERON

摘要

The invention is directed to methods for treating autoimmune diseases such as multiple sclerosis by orally administering a bystander antigen such as myelin basic protein or proteolipid protein in conjunction with a polypeptide having Type I interferon activity in such a manner as to induce oral tolerance to the bystander antigen resulting in suppression of the autoimmune response.