摘要 |
<p>The invention is concerned with the compounds having formula (I), the pharmaceutically acceptable acid addition salts and the stereochemically isomeric form thereof, wherein X and Y are CH or N; R?1, R2 and R3¿ are hydrogen or C¿1-4? alkyl; R?4 and R5¿ are hydrogen, halo, C¿1-4? alkyl, C1-4 alkyloxy, hydroxy, trifluoromethyl, trifluoromethyloxy or difluoromethyloxy; R?6¿ is C¿1-6? alkyl, hydroxy C1-6 alkyl, C1-4 alkyloxy C1-6 alkyl, phenyl or phenyl C1-4 alkyl; Z is C=O or CHOH; and (a) is a radical of formula (a-1), (a-2), (a-3), (a-4), (a-5), (a-6) or (a-7); compositions comprising said compounds, processes for preparing the same and the use of these compounds for treating Helicobacter related diseases.</p> |