发明名称 |
Reagens für schnelle Peptidsynthese. |
摘要 |
<p>This invention relates to compounds of the formula: <CHEM> wherein R is an electron withdrawing group; R1 is H or COZ; X1 and X2 are independently H, lower alkyl, aryl, aryl lower-alkyl or polystyrene or R and X1 taken together with the carbon atoms to which they are attached form a ring containing from 4 to 15 ring carbon atoms and may contain up to 2 heteroatoms, wherein the heteroatoms are O, S, or N; and Z is an amino acid residue, a peptide residue or a leaving group. The compounds of the present invention are adaptable as blocking or protecting groups for an amine composition useful in peptide synthesis. The present invention is also directed to a method of protecting an amino group of an organic molecule during a reaction which modifies a portion of the molecule other than the protected amino group.</p> |
申请公布号 |
DE69022293(D1) |
申请公布日期 |
1995.10.19 |
申请号 |
DE1990622293 |
申请日期 |
1990.06.07 |
申请人 |
RESEARCH CORP. TECHNOLOGIES, INC., TUCSON, ARIZ., US |
发明人 |
CARPINO, LOUIS A., AMHERST, MASS. 01003, US;PHILBIN, MICHAEL, PLAINSBORO, N.J. 08536, US |
分类号 |
C07D333/16;C07C69/96;C07C271/28;C07C317/08;C07C317/14;C07C317/18;C07C317/48;C07C321/18;C07C321/28;C07C323/14;C07D333/64;C07F7/08;C07K1/04;C07K1/06;C07K1/113;C07K5/06;C07K5/08;C07K14/575;C07K14/655;(IPC1-7):C07C317/18;C07D333/56;C07D213/30;C07D271/10;C07C317/04;C07C317/10;C07C271/34;C07K5/04;C07C69/732;C07C271/26 |
主分类号 |
C07D333/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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