| 发明名称 |
METHODS FOR DETERMINING SUSCEPTIBILITY TO LEAD POISONING. |
| 摘要 |
A method is disclosed for detecting a polymorphism in the delta -aminolevulinate dehydratase gene which is associated with an altered susceptibility to lead poisoning. A point mutation which generates an MspI restriction endonuclease recognition site was found in the ALAD2 allele of the delta -aminolevulinate dehydratase gene which is not present in the ALAD1 allele. Kit containing primers for the amplification of the polymorphic region of the ALAD gene are provided. |
| 申请公布号 |
EP0603205(A4) |
申请公布日期 |
1995.10.18 |
| 申请号 |
EP19920916858 |
申请日期 |
1992.07.30 |
| 申请人 |
MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK |
发明人 |
DESNICK, ROBERT, J.;WETMUR, JAMES, G. |
| 分类号 |
A01K67/027;C12N1/19;C12N1/21;C12N5/10;C12N9/88;C12N15/09;C12Q1/68;(IPC1-7):C12Q1/68;C07H21/04;C12N15/00;C12N15/12;C12N5/06;C12P19/34 |
主分类号 |
A01K67/027 |
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