Thieno[3,2-F][1,2,4]triazolo[4,3-A][1,4]diazepine derivatives as PAF antagonists.

摘要

A triazolo-1,4-di-azepine compound of the below given formula and a pharmacologically acceptable salt thereof are disclosed and useful in the pharmaceutical field, especially to allergic diseases.
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in which R1 and R2 are hydrogen or an alkyl, R3 is hydrogen or a halogen, R4 is hydrogen or an alkyl, X is -OCO-, -NHCO-, -CO- or others and Y is a cycloalkyl, a cycloalkylalkyl, an alkynyl or others.
with the proviso that when R₁ is hydrogen then R₂ cannot be methyl.