发明名称 Process for the preparation of 2-halogeno-5-cyano pyridines
摘要 The title compounds of the formula <IMAGE> (I) can be prepared by reacting methylene-glutaconic acid dinitriles of the formula R1-CH=C(CN)-CH'CH-CN (II) with hydrogen halide of the formula HX (III) In these formulae, X denotes fluorine, chlorine, bromine or iodine and R1 denotes -OR2 or -N(R2, R3), in which R2 and R3, independently of one another, represent straight-chain or branched C1-C8-alkyl, C3-C8-alkenyl, C2-C8-alkoxyalkyl, C4-C8-alkoxyalkenyl, C3-C8-cycloalkyl, C6-C12-aryl, C7-C10-aralkyl or a 5- to 8-membered saturated or unsaturated heterocyclic ring containing 1 or 2 heteroatoms from the group comprising N, O and S, where R2 and R3, with the N atom on which they are substituents, may also form a 5- to 8-membered ring which may contain a further heteroatom from the group comprising N, O and S.
申请公布号 US5459273(A) 申请公布日期 1995.10.17
申请号 US19940207734 申请日期 1994.03.08
申请人 BAYER AKTIENGESELLSCHAFT 发明人 KRAUS, HELMUT;TRAENCKNER, HANS-JOACHIM
分类号 C07D213/85;(IPC1-7):C07D413/04;C07D213/09;C07D213/84 主分类号 C07D213/85
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