发明名称 |
Arylbicyclooctanes as inhibitors of leukotriene biosynthesis |
摘要 |
Compounds having the formula I: <IMAGE> I are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
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申请公布号 |
US5459271(A) |
申请公布日期 |
1995.10.17 |
申请号 |
US19930094814 |
申请日期 |
1993.07.20 |
申请人 |
MERCK FROSST CANADA, INC. |
发明人 |
FRIESEN, RICHARD W.;GIRARD, YVES;DUBE, DANIEL |
分类号 |
C07D493/08;(IPC1-7):C07D407/04;C07D409/04;C07D215/22;A61K31/47 |
主分类号 |
C07D493/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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