New (((tetra:hydro:quinolin-8-yl)-sulphonyl:amino)-oxo-(imidazolyl)pentyl)piperidine(s)

摘要

Imidazolyl oxopentyl piperidine derivs. of formula (I), their salts and diastereoisomers, are new. R = -CONHCH2R3, ((phenyl(1-4C)alkoxy) amino)carbonyl, -CH2OCOR4, -CH2SO2R5 or -COYCH2R6; R1, R2 = H or methyl; R3 = phenyl(1-4C)alkyl, phenoxy(1-6C)alkyl, oxo(piperidin-1-yl)(1-4C)alkyl, or oxo(phenyl(1-4C)alkyl)amino(1-4C)alkyl; R4 = trifluorooxo(1-4C)alkyl, 2-oxocyclopentyl, phenyl(1-4C)alkyl, or 3-8C cycloalkyl(1-4C)alkyl; R5, R6 = phenyl(1-4C)alkyl; Y = hydroxyamino or methylene.