Novel ligands that bind Eph family receptors are identified, and methods for making the soluble ligands in biologically active form are described. cDNA clones encoding these novel proteins enable production of the recombinant proteins, which are useful to support neuronal and other receptor-bearing cell populations.
申请公布号
WO9527060(A2)
申请公布日期
1995.10.12
申请号
WO1995US04208
申请日期
1995.04.04
申请人
REGENERON PHARMACEUTICALS, INC.
发明人
DAVIS, SAMUEL;GALE, NICHOLAS;ALDRICH, THOMAS, H.;MAISONPIERRE, PETER, C.;GOLDFARB, MITCHELL;YANCOPOULOS, GEORGE, D.