| 发明名称 |
CYTOTOXIC T-CELL LYMPHOCYTE (CTL) ACTIVITY REGULATION BY CLASS I MHC PEPTIDES |
| 摘要 |
Fragments from the polymorphic domains of Class I HLA antigen domains are used to modulate T-cell activity. The peptides are from the alpha 1- or alpha 2-domains, particularly of the HLA-A, and B antigens. The peptides may be conjugated to other compounds to be used in diagnosis and therapy. The peptides may block lysis, CTL proliferation or have other regulating effects.
|
| 申请公布号 |
WO9526979(A1) |
申请公布日期 |
1995.10.12 |
| 申请号 |
WO1995US04349 |
申请日期 |
1995.04.05 |
| 申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO |
发明人 |
CLAYBERGER, CAROL;KRENSKY, ALAN, M.;PARHAM, PETER |
| 分类号 |
A61K38/00;A61K31/395;A61K39/00;A61P37/06;C07K7/06;C07K7/08;C07K14/74;G01N33/569;(IPC1-7):C07K7/00;A61K38/04 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
