Methods of treating hypotension and septic shock by introducing into a mammal suspected of needing such treatment an effective amount of transforming growth factor- beta or an active fragment thereof to inhibit transcription of a gene encoding inducible nitric oxide synthase but not a gene encoding constitutive nitric oxide synthase.
申请公布号
WO9526745(A1)
申请公布日期
1995.10.12
申请号
WO1994US03705
申请日期
1994.04.05
申请人
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;LEE, MU-EN;PERRELLA, MARK, A.