发明名称 TRANSFORMING GROWTH FACTOR- beta INHIBITS INDUCIBLE NITRIC OXYDE SYNTHASE GENE TRANSCRIPTION
摘要 Methods of treating hypotension and septic shock by introducing into a mammal suspected of needing such treatment an effective amount of transforming growth factor- beta or an active fragment thereof to inhibit transcription of a gene encoding inducible nitric oxide synthase but not a gene encoding constitutive nitric oxide synthase.
申请公布号 WO9526745(A1) 申请公布日期 1995.10.12
申请号 WO1994US03705 申请日期 1994.04.05
申请人 PRESIDENT AND FELLOWS OF HARVARD COLLEGE;LEE, MU-EN;PERRELLA, MARK, A. 发明人 LEE, MU-EN;PERRELLA, MARK, A.
分类号 A61K38/18;C07K14/495;(IPC1-7):A61K38/02;A61K38/04;C07K7/00;C07K14/00;C07K16/44 主分类号 A61K38/18
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