发明名称 THIENOPYRANE DERIVATIVES, METHOD OF THEIR PRODUCTION AND THEIR USE
摘要 Theinopyrane derivatives of general formula I, where thiophene surplus can be substituted with -CN, -CHO, -CH=NOH, -CONH2 or -COOR1, R1 means alkyl with 1 to 4 atoms of carbon, n means integer 3, 4 or 5. These derivatives can be gained with reaction of compound with general formula III, where X means chlorine, bromine or iodine with compound of general formula IV, where n means integer 3, 4 or 5 in inert organic diluent by presence at least 2 equivalents of strong nucleophile base and this way gained racemate can be divided on enantiomers. Compounds are suitable for treating of illnesses which can be treated by activation of membrane canals K+.
申请公布号 SK278012(B6) 申请公布日期 1995.10.11
申请号 SK19900003172 申请日期 1990.06.26
申请人 BINDER DIETER;ROVENSZKY FRANZ;WEINBERGER JOSEF;FERBER HUBERT 发明人 BINDER DIETER;ROVENSZKY FRANZ;WEINBERGER JOSEF;FERBER HUBERT
分类号 A61K31/38;A61K31/45;C07D405/04;C07D495/04;(IPC1-7):C07D495/04 主分类号 A61K31/38
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