| 摘要 |
A method for treating a disease and drug units for use in performing such method. The method involves invading and flooding select cells of a living being with a drug or medical material to correct a genetic flaw, destroy or otherwise prevent the production or multiplication of a disease defining substance such as a virus in such cells or prevent the cells from uncontrollably growing or dividing. The method involves injecting or otherwise administering a dose of drug units to the body or bloodstream of a living being and targeting such drug units to the select cells to be treated and invaded with the drug of the units. In a preferred form, the drug is a derivative of vitamin A, such as 13-cis retinoic acid or other synthetic retinoid, which operates upon invading and flooding immature or precancerous white blood cells to restore the regulatory apparatus which they lack permitting them to mature normally and perform their normal functions such as their formation of platelets and preventing them from multiplying uncontrollably. The method involves forming such drug units of a small quantity of such drug, preferably encapsulated in a microcapsule or biodegradeable material and containing one or more targeting particles attached thereto for targeting or attaching the drug unit to the desired immature or diseased cell to be treated with the drug upon its attachment and release to the select cell to which the drug unit targets. In a particular form, select doses of such drug units are intermittently administered to the body or bloodstream by timed controlled administration of such select doses and/or by their timed release from a body implant employing biodegradation or other mechanism to effect such timed dose or drug unit release. In another form, the implant contains or is connected to a computer and includes means for detecting the presence and quantity or level of the cells requiring treatment, wherein the computer effects and controls the release of select quantities of such targeting drug units to the body or bloodstream in accordance with the information computed by the computer.
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