| 发明名称 |
Thrombin receptor radioligands |
| 摘要 |
The radioligands are six amino acid peptides having iodinated tyrosine at amino acid position six, including Ala-pFPhe-hArg-Cha-hArg-Tyr(I)-NH2, which mimic the activated form of the thrombin receptor protein. Thrombin receptor radioligands of the present invention are useful for screening for thrombin receptor antagonists.
|
| 申请公布号 |
US5457177(A) |
申请公布日期 |
1995.10.10 |
| 申请号 |
US19930077850 |
申请日期 |
1993.06.16 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
VEBER, DANIEL F.;NUTT, RUTH F.;FENG, DONG-MEI;GOULD, ROBERT J.;CONNOLLY, THOMAS M. |
| 分类号 |
G01N33/53;A61K51/08;C07K7/06;C07K14/705;C07K14/745;G01N33/566;(IPC1-7):C07K7/06;A61K38/08 |
主分类号 |
G01N33/53 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
