N-SUBSTITUTED INDOLE DERIVATIVE.

摘要

The object is to provide a compound having potent and persistent effects of lowering blood pressure and ameliorating urination disorder by blocking alpha 1-adrenergic receptor. An N-substituted indole derivative represented by general formula (I) and an acid-addition salt thereof, wherein R<1> represents alkyl, or phenyl which may be substituted by halogen, alkyl or alkoxy; R<2> represents phenyl which may be substituted by one or two groups selected from among halogen, alkyl, alkoxy and 1-piperidyl, or 2-pyridyl which may be substituted by one or two groups selected from among halogen, alkyl and alkoxy; and n represents an integer of 2 to 5. <CHEM>