发明名称 Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
摘要 Copolymers of poly(alkylene oxides) and amino acids or peptide sequences are disclosed, which amino acids or peptide sequences have pendant functional groups that are capable of being conjugated with pharmaceutically active compounds for drug delivery systems and cross-linked to form polymer matrices functional as hydrogel membranes. The copolymers can also be formed into conductive materials. Methods are also disclosed for preparing the polymers and forming the drug conjugates, hydrogel membranes and conductive materials.
申请公布号 US5455027(A) 申请公布日期 1995.10.03
申请号 US19930023069 申请日期 1993.02.25
申请人 ENZON, INC. 发明人 ZALIPSKY, SAMUEL;BOLIKAL, DURGADAS;NATHAN, ARUNA;KOHN, JOACHIM B.
分类号 A61K47/30;A61K47/48;A61K49/00;A61L15/26;A61L27/18;C08G63/685;C08G65/32;C08G69/10;C08G69/40;C08G69/44;C08G81/00;H01M6/18;(IPC1-7):A61K31/74;A61K31/765;A61K31/785 主分类号 A61K47/30
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