A DNA which codes for the variable region of the anti-human influenza A type virus antibody recognizing the H,N, and H2N2 subtypes of haemagglutinin.

摘要

A DNA coding for the variable region of the anti-human influenza A type virus antibody having the following characteristics (a) and (b); (a) recognizing the stem region of haemaggulutinin molecule of the H1N1 and H2N2 subtypes of human influenza A type virus but not recognizing the stem region of haemaggulutinin molecule of the H3N2 subtype thereof; and (b) having a neutralization activity for the H1N1 and H2N2 subtypes of human influenza A type virus but no neutralization activity for the H3N2 subtype thereof. A DNA coding for CDR in the above-mentioned DNA. This DNA is usable in the production through genetic engineering techniques and in the diagnosis and treatment.