GENE-THERAPEUTIC PROCESS USING ANTIBIOTIC-RESISTANCE GENE-FREE DNA VECTORS

摘要

Use of a vector DNA for the production of a pharmaceutical agent for the treatment of mammals or humans by gene therapy in which the vector DNA causes a modulation, correction or activation of the expression of an endogenous gene or the expression of a gene introduced into the cells of the mammal or human by the vector DNA, which is characterized in that the vector nucleic acid does not contain an active antibiotic resistance gene or one which is relevant for humans. Such a vector DNA is particularly suitable for treatment of the respiratory tract, the intestinal tract and the skin by gene therapy.