The present invention provides a method of preferentially selecting for the growth of normal cells in mixed cultures. The method involves culturing the mixed culture in a medium lacking pyruvate but including carnosine or anserine. The carnosine or anserine is used at a concentration at which the growth of the transformed and/or cancer cells is substantially prevented in the absence of pyruvate but at which normal cells will continue to grow in the absence of pyruvate.
申请公布号
WO9525515(A1)
申请公布日期
1995.09.28
申请号
WO1995AU00158
申请日期
1995.03.22
申请人
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR;HOLLIDAY, ROBIN;MCFARLAND, GAIL, ANNETTE